We describe the clinical, neuroimaging, electrophysiological, and neuropsychological characteristics of three patients fulfilling the proposed criteria for TEA, initially referred to our memory clinic for evaluation and treatment of probable dementia. Transient epileptic amnesia (TEA) is a recently described, typically misdiagnosed at presentation, distinctive syndrome, characterized by recurrent, brief attacks of memory loss in middle-aged or elderly people, accompanied by significant interictal memory difficulties. H., & Karacostas D.Īged, Amnesia, Anticonvulsants, Brain, Electroencephalography, Epilepsy, Female, Humans, Magnetic Resonance Angiography, Male, Middle Aged, Neuropsychological Tests, Tomography, X-Ray Computed Ioannidis, P., Balamoutsos G., Karabela O., Kosmidis M. A study of 153 cases.Transient epileptic amnesia in a memory clinic setting: a report of three cases. Syndromes of transient amnesia: towards a classification. Long-Term Outcome in Patients With Transient Global Amnesia: A Population-Based Study.Mayo Clin Proc. Risk factors of transient global amnesia - Three case reports. Transient global amnesia: current perspectives.Neuropsychiatr Dis Treat. no specific treatment is indicated for a typical episodeĬlassical diseases revisited: transient global amnesia.No recent history of head trauma or seizures must be present No focal neurology or epileptic features must be present No loss of personal identity must be present No cognitive impairment other than amnesia must be present No alteration in consciousness must be present a population-based study concluded that an episode of TGA does not increase the risk of subsequent cerebrovascular events, seizures, or cognitive impairment (4)Īcute onset of anterograde amnesia must be present.There is no excess of cerebrovascular disease in patients with TGA There is a correlation between TGA and migraine. diagnosis may be made safely in the presence of a characteristic collateral history.remote precipitating events, with onset reported weeks prior to TGA, are considered anxiety triggered by conflict at home or work, health problems, and financial stressors (3).close precipitating events for TGA are considered emotional stress (i.e., triggered by gastric endoscopy, birth/death announcement, and difficult/exhausting workday), physical effort (i.e., gardening, house work, and sawing wood), physical exertion (including sexual activity), and water contact/temperature change (i.e., hot bath/shower and cold swim) (3).possible that it may result from different mechanisms such as venous congestion with valsalva-like activities before symptom onset, arterial thromboembolic ischaemia and vasoconstriction due to hyperventilation (1).Precipitating factors include sexual intercourse and heavy physical exercise, particularly swimming in cold water. study evidence showed a recurrence rate of 6.3% in a 10 year period.studies show a slight female predominance.Across studies, the mean age of an episode ranges from 61 to 67.3 years most commonly presents in the seventh decade of life. attacks usually last for 1-8 h but should be less than 24 h (1)Įpidemiological data put the annual incidence of TGA between 3.4 and 10.4/100,000 (2).
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